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Conciente de la falta de datos científicos serios, la Food and Drug Administration junto a la Universidad de Pennsilvania realizaron un encuentro en octubre del 2009, de los cuales derivó la iniciativa de unir esfuerzos públicos y privados para, entre otros, desarrollar nuevas drogas en este campo.Los artículos publicados en este ejemplar también derivan de dicha reunión.Scholz y Yaksh dedican sus letras a la investigación preclínica del tema, la dificultad para establecer una definición precisa, los posibles mecanismos involucrados en su génesis, los modelos animales usados y los criterios mínimos para avanzar en su conocimiento.Kehlet y Rathmell se encargan de ahondar, en forma sucinta pero contundente, respecto a lo que se sabe de DPP, las limitaciones de los estudios hasta ahora publicados y las líneas que debieran seguirse para su investigación. en su artículo “Previniendo el DPP” se abocan a desglosar aquellos factores que consideran deben ser analizados para establecer la real importancia clínica de los resultados obtenidos de investigaciones sobre el tema.La revista Anesthesiology en su número de marzo dedica cuatro editoriales al tema de dolor persistente post-quirúrgico (DPP), en un afán por dar impulso científico serio a su estudio y tratamiento.Si bien la presencia de DPP se reconoce desde hace años, poco se sabe de su patogenia y nada respecto a recomendaciones para su prevención.A woman who has only one picture posted, is wearing a tight bikini and making an overly suggestive pose are usually clear signals to steer clear.Another clue of a pretender is a woman who has a poorly written profile.

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